Mounjaro vs Wegovy vs the Wegovy pill
The three treatments below are the licensed weight-loss options UK online providers actually sell. They work in related ways but differ meaningfully on results, routine and cost. One direct comparison exists: in the SURMOUNT-5 trial, tirzepatide (Mounjaro) averaged around 20% body-weight loss against around 14% on semaglutide 2.4 mg (Wegovy).
| Mounjaro Most weight loss | Wegovy Most established | Wegovy Pill Needle-free | |
|---|---|---|---|
| Medicine | Tirzepatide — a dual GIP + GLP-1 receptor agonist, the only dual-hormone option | Semaglutide — a GLP-1 receptor agonist with the longest UK track record | Oral semaglutide — the same hormone pathway as Wegovy, in tablet form |
| Routine | One injection a week, pre-filled KwikPen | One injection a week, pre-filled pen | One tablet every morning, empty stomach, 30-minute wait before eating |
| Trial results | ≈21–22% average body-weight loss at the higher doses over 72 weeks (SURMOUNT-1) | ≈15% average over 68 weeks at 2.4 mg (STEP 1); also shown to cut cardiovascular risk (SELECT) | ≈13.6% average over 64 weeks at 25 mg (OASIS 4); ≈16.6% among consistent takers |
| Dose ladder | 2.5 mg → 15 mg, stepping up roughly every 4 weeks | 0.25 mg → 2.4 mg over about 16 weeks; a 7.2 mg dose was approved in January 2026 | 1.5 mg → 25 mg over about 12 weeks |
| Common side effects | Nausea, diarrhoea, constipation, vomiting, tiredness | Nausea (around 4 in 10), diarrhoea, vomiting, constipation, headache | Nausea, diarrhoea, constipation, vomiting, headache |
| Starter dose from | £145.99 / 4 weeks (2.5 mg) | £79.97 / 4 weeks (0.25 mg) | £99 / 4 weeks (1.5 mg) |
| Maintenance dose from | £173.99 (5 mg) · £288.99 (15 mg) | £174.99 (2.4 mg) | £190 (25 mg) |
Trial figures are averages from each medicine's headline study and are not a promise of individual results. Prices are the lowest listed by the 24 regulated providers we track, as of 4 July 2026.
What each injection costs, provider by provider
Every provider below is a GPhC-registered pharmacy or CQC-regulated clinic dispensing the same licensed medicines. Pick a treatment — each table shows the starter dose, sorted by ongoing price, with first-order promotions shown where a provider lists one. Our recommended provider is pinned at the top and clearly marked; everyone beneath is in strict price order.
Mounjaro (tirzepatide) — 2.5 mg starter dose
24 providers · price per pen (4 weekly doses) · prices last checked 4 July 2026
| Provider | Price / 4 weeks | Delivery | Consultation & support | Code | |
|---|---|---|---|---|---|
| The Weight Clinic ★ RecommendedGPhC-registered pharmacy | £160 / 4 wks£125 first month with NEWME | Next-day delivery · needles included | Free consult · video reviews monthly · refund if declined | NEWME£35 off first order | Visit site → |
| Click2PharmacyGPhC-registered pharmacy | £145.99 / 4 wks | £3.99 next-day · cold-chain | Free consult · needles & wipes with 1st order | C2P20first orders | Visit site → |
| Chemist4UGPhC-registered pharmacy | £148 / 4 wks£122 first month with NEW26 | Free over £39 · cold-chain | Free consult · needles & sharps bin included | NEW26£26 off new patients | Visit site → |
| Oxford Online PharmacyGPhC-registered pharmacy | £148.96 / 4 wks£128.96 first month with W2TM539S | £4.99 tracked | Free ~3-min assessment · no fee | W2TM539S£20 off over £99 | Visit site → |
| ASDA Online DoctorCQC-regulated (ZAVA) | £148.97 / 4 wks£138.97 first month with WNLC10A | Paid next-day cold-chain · free collect | Free online consultation · no separate fee | WNLC10A£10 off first order | Visit site → |
| PharmicaGPhC-registered pharmacy | £159.99 / 4 wks | Free tracked · next-day avail. | Free consult · lowest-price guarantee | — | Visit site → |
| Cloud PharmacyGPhC-registered · UK-based | £164.99 / 4 wks£154.99 first month with NEWME10 | Free next-day | Free consult · needles included | NEWME10~£10 off first order | Visit site → |
| PrivateDocGPhC pharmacy + CQC clinic | £167 / 4 wks | From £4.50 · usually next-day | Free consult · reviewed in ~4 hours | — | Visit site → |
| Phlo ClinicGPhC-registered pharmacy | £169 / 4 wks£149 first month with first order | Free tracked · cold-chain | Free consult · monthly check-ins + dietitian | Price matchbeats any lower price | Visit site → |
| Simple Online PharmacyGPhC-registered pharmacy | £169 / 4 wks | Free over £45 | Free consult · dietitian & coach team | — | Visit site → |
| myBMIGPhC-registered prescribers | £169 / 4 wks | Free single · £8.95 bundle | Package · includes anti-nausea meds | — | Visit site → |
| Pharmacy2UGPhC pharmacy + CQC-regulated | £169.99 / 4 wks£124.99 first month with first-order code | Free over £30 · next-day paid | Free consult · coaching + 12-mo aftercare | — | Visit site → |
| ZAVACQC-regulated service | £169.99 / 4 wks£129.99 first month with WZUK40 | Free next-day · cold packaging | Free consult · ongoing clinician support | WZUK40£40 off new customers | Visit site → |
| Superdrug Online DoctorGPhC pharmacy + CQC-regulated | £176 / 4 wks£156 first month with WLNP20 | Free home / collect · £3.99 next-day | Free questionnaire · pay if prescribed | WLNP20£20 off first order | Visit site → |
| Boots Online DoctorGPhC pharmacy + CQC-regulated | £176.97 / 4 wks | Free tracked (2–3 day) · cold-chain | Free consult with photo check · no fee | — | Visit site → |
| LloydsPharmacy Online DoctorGPhC pharmacy + CQC-regulated | £179.99 / 4 wks£149.99 first month with START30 | Next-day £5.95 · cold-chain · needles inc. | Free questionnaire · pay only if prescribed | START30£30 off over £99 | Visit site → |
| MedExpressGPhC-registered pharmacy | £179.99 / 4 wks£139.99 first month with new-customer offer | From £2.90 · express £3.95 | Free consult · no prescription fee | — | Visit site → |
| Simply Meds OnlineGPhC-registered pharmacy | £179.99 / 4 wks | Free UK postage | Free consult · no hidden fees | — | Visit site → |
| The Independent PharmacyGPhC + CQC + NHS-registered | £179.99 / 4 wks£152.99 first month with NEW15 | From £2.99 tracked | Free consult · pay-per-order, no tie-in | NEW1515% off first order | Visit site → |
| CheqUpGPhC + CQC · LegitScript | £189 / 4 wks | Free · 1–3 days | Free consult · 1:1 coaching included | — | Visit site → |
| JuniperGPhC-registered dispensing | £199 / 4 wks | Free · every 4 weeks | Programme · app tracking + prescriber | SNOWMANwelcome offer | Visit site → |
| VoyGPhC pharmacy + CQC-regulated | £214 / 4 wks£139 first month with first month | Free next-day · discreet packaging | Free consult · coaching app | — | Visit site → |
| NumanGPhC + CQC-regulated | £219 / 4 wks | Free next-day · cooled packaging | Free consult · subscription plan | — | Visit site → |
| Second NatureGPhC pharmacy + CQC-regulated | £229 / 4 wks£179 first month with auto £50 off | Included in programme | Programme · personal health coach + app | Auto £50 offfirst month, no code needed | Visit site → |
Wegovy (semaglutide) — 0.25 mg starter dose
24 providers · price per pen (4 weekly doses) · prices last checked 4 July 2026
| Provider | Price / 4 weeks | Delivery | Consultation & support | Code | |
|---|---|---|---|---|---|
| The Weight Clinic ★ RecommendedGPhC-registered pharmacy | £115 / 4 wks£80 first month with NEWME | Next-day delivery · needles included | Free consult · video reviews monthly · refund if declined | NEWME£35 off first order | Visit site → |
| Boots Online DoctorGPhC pharmacy + CQC-regulated | £79.97 / 4 wks | Free tracked (2–3 day) · cold-chain | Free consult with photo check · no fee | — | Visit site → |
| Oxford Online PharmacyGPhC-registered pharmacy | £88.96 / 4 wks£68.96 first month with W2TM539S | £4.99 tracked | Free ~3-min assessment · no fee | W2TM539S£20 off over £99 | Visit site → |
| ASDA Online DoctorCQC-regulated (ZAVA) | £88.97 / 4 wks£78.97 first month with WNLC10A | Paid next-day cold-chain · free collect | Free online consultation · no separate fee | WNLC10A£10 off first order | Visit site → |
| PrivateDocGPhC pharmacy + CQC clinic | £97 / 4 wks | From £4.50 · usually next-day | Free consult · reviewed in ~4 hours | — | Visit site → |
| Chemist4UGPhC-registered pharmacy | £99 / 4 wks£73 first month with NEW26 | Free over £39 · cold-chain | Free consult · needles & sharps bin included | NEW26£26 off new patients | Visit site → |
| Simple Online PharmacyGPhC-registered pharmacy | £99 / 4 wks | Free over £45 | Free consult · dietitian & coach team | — | Visit site → |
| Superdrug Online DoctorGPhC pharmacy + CQC-regulated | £99 / 4 wks£79 first month with WLNP20 | Free home / collect · £3.99 next-day | Free questionnaire · pay if prescribed | WLNP20£20 off first order | Visit site → |
| The Independent PharmacyGPhC + CQC + NHS-registered | £99.79 / 4 wks£84.82 first month with NEW15 | From £2.99 tracked | Free consult · pay-per-order, no tie-in | NEW1515% off first order | Visit site → |
| LloydsPharmacy Online DoctorGPhC pharmacy + CQC-regulated | £99.99 / 4 wks£69.99 first month with START30 | Next-day £5.95 · cold-chain · needles inc. | Free questionnaire · pay only if prescribed | START30£30 off over £99 | Visit site → |
| MedExpressGPhC-registered pharmacy | £99.99 / 4 wks£59.99 first month with new-customer offer | From £2.90 · express £3.95 | Free consult · no prescription fee | — | Visit site → |
| Simply Meds OnlineGPhC-registered pharmacy | £99.99 / 4 wks | Free UK postage | Free consult · no hidden fees | — | Visit site → |
| ZAVACQC-regulated service | £99.99 / 4 wks£59.99 first month with WZUK40 | Free next-day · cold packaging | Free consult · ongoing clinician support | WZUK40£40 off new customers | Visit site → |
| Click2PharmacyGPhC-registered pharmacy | £109 / 4 wks | £3.99 next-day · cold-chain | Free consult · needles & wipes with 1st order | C2P20first orders | Visit site → |
| Cloud PharmacyGPhC-registered · UK-based | £114.99 / 4 wks£104.99 first month with NEWME10 | Free next-day | Free consult · needles included | NEWME10~£10 off first order | Visit site → |
| Phlo ClinicGPhC-registered pharmacy | £119 / 4 wks£89 first month with first order | Free tracked · cold-chain | Free consult · monthly check-ins + dietitian | Price matchbeats any lower price | Visit site → |
| myBMIGPhC-registered prescribers | £119 / 4 wks | Free single · £8.95 bundle | Package · includes anti-nausea meds | — | Visit site → |
| Pharmacy2UGPhC pharmacy + CQC-regulated | £119.28 / 4 wks | Free over £30 · next-day paid | Free consult · coaching + 12-mo aftercare | — | Visit site → |
| PharmicaGPhC-registered pharmacy | £119.99 / 4 wks | Free tracked · next-day avail. | Free consult · lowest-price guarantee | — | Visit site → |
| CheqUpGPhC + CQC · LegitScript | £129 / 4 wks | Free · 1–3 days | Free consult · 1:1 coaching included | — | Visit site → |
| VoyGPhC pharmacy + CQC-regulated | £144 / 4 wks£69 first month with first month | Free next-day · discreet packaging | Free consult · coaching app | — | Visit site → |
| NumanGPhC + CQC-regulated | £149 / 4 wks | Free next-day · cooled packaging | Free consult · subscription plan | — | Visit site → |
| Second NatureGPhC pharmacy + CQC-regulated | £159 / 4 wks£109 first month with auto £50 off | Included in programme | Programme · personal health coach + app | Auto £50 offfirst month, no code needed | Visit site → |
| JuniperGPhC-registered dispensing | £164 / 4 wks | Free · every 4 weeks | Programme · app tracking + prescriber | SNOWMANwelcome offer | Visit site → |
Wegovy Pill (oral semaglutide) — 1.5 mg starter dose
2 providers list it so far (it launched recently) · price per 4 weeks · prices last checked 4 July 2026
| Provider | Price / 4 weeks | Delivery | Consultation & support | Code | |
|---|---|---|---|---|---|
| The Weight Clinic ★ RecommendedGPhC-registered pharmacy | £115 / 4 wks£80 first month with NEWME | Next-day delivery · needles included | Free consult · video reviews monthly · refund if declined | NEWME£35 off first order | Visit site → |
| Chemist4UGPhC-registered pharmacy | £99 / 4 wks | Free over £39 · cold-chain | Free consult · needles & sharps bin included | NEW26£26 off new patients | Visit site → |
A plain-English note on this table: all listed providers are GPhC- or CQC-regulated; prices move, so always confirm the current figure on the provider's own site before ordering; and this listing is price information, not an offer to supply medicine.
Why The Weight Clinic is the provider we recommend
Cheapest is easy to find — it's the top of every table above. We recommend The Weight Clinic on the things the price column can't show: a monthly video review with a clinician rather than a tick-box form, a refund if the prescriber turns you down, and next-day delivery with needles included. It stocks all three treatments on this page — Mounjaro from £160 for 4 weeks, Wegovy from £115, the Wegovy pill from £115 — and it's the cheapest listed provider for the pill at the full 25 mg dose. The code NEWME takes £35 off a first order.
Check your eligibility at The Weight Clinic → Prescription-only: a clinician reviews your suitability first, and can say no. If declined, you get your money back.How to choose between them: five questions
There is no single best weight-loss injection — there's a best fit for your situation. Work through these five questions in order and the field usually narrows itself. Our full decision framework goes deeper on each one.
Needle or tablet?
If a weekly injection is a dealbreaker, the Wegovy pill is the only needle-free option — but it demands a strict empty-stomach morning routine, every day.
How much loss are you aiming for?
Trial averages rank Mounjaro highest (≈21–22% at top doses), Wegovy next (≈15%), the pill close behind (≈13.6%). If you need substantial loss, that ordering matters.
What's your budget at maintenance dose?
Starter prices flatter every option. Compare at the dose you'll stay on: Mounjaro 15 mg from £288.99, Wegovy 2.4 mg from £174.99, the pill at 25 mg from £190 per 4 weeks.
How do you weigh side effects?
All three share the same gut-related profile — nausea, constipation, diarrhoea — worst during dose increases. A slower ladder (Wegovy's 16 weeks) can be gentler than a faster one.
How much support do you want?
The medicine is identical between providers; the humans aren't. If you want a clinician reviewing your progress monthly, weigh that as heavily as the price column.
Then let the prescriber decide
Whatever you conclude, these are prescription-only medicines. The prescriber confirms eligibility (typically BMI 30+, or 27+ with a weight-related condition) and can recommend differently.
Frequently asked questions
Which weight-loss injection produces the most weight loss?
On trial averages, Mounjaro (tirzepatide) currently leads: around 21–22% of body weight at the higher doses over 72 weeks in SURMOUNT-1, versus roughly 15% for Wegovy (semaglutide 2.4 mg) over 68 weeks in STEP 1 and about 13.6% for the Wegovy pill over 64 weeks. In the one direct head-to-head trial, SURMOUNT-5, tirzepatide averaged about 20% against about 14% on semaglutide. These are averages — individual results vary widely, and the biggest medicine is not automatically the right one for you.
Is the medicine the same whichever provider I order from?
Yes. Every regulated UK provider dispenses the same manufacturer-made, UK-licensed pens and tablets. What differs is the price, the consultation model, the support included and the delivery arrangements — which is exactly why a like-for-like comparison saves money.
How much does a weight-loss injection cost per month in the UK?
At starter doses, Mounjaro 2.5 mg is listed from £145.99 for 4 weeks and Wegovy 0.25 mg from £79.97. The catch is that starter doses are temporary: maintenance doses cost more — Mounjaro 15 mg from £288.99 and Wegovy 2.4 mg from £174.99 per 4 weeks. Budget for the dose you will settle on, not the first month.
Can I buy a weight-loss injection without a prescription?
No. Mounjaro, Wegovy and the Wegovy pill are prescription-only medicines in the UK. A prescriber must assess you first and can decline. Anyone selling these medicines without a prescription — or offering "compounded" copies — is operating outside UK regulation, and what they ship may be unsafe. We only list GPhC- or CQC-regulated providers.
Who is eligible for weight-loss injections in the UK?
UK providers typically require a BMI of 30 or above, or 27 and above alongside a weight-related condition such as high blood pressure or type 2 diabetes. Most now ask for photo or video verification of your weight, and the final decision always rests with the prescriber.
Why is The Weight Clinic your recommended provider?
Three concrete reasons from its listing: monthly video reviews with a clinician rather than a quick form, a refund if the prescriber declines you, and the NEWME code giving £35 off a first order. Its ongoing prices sit mid-table for the injections and it is the cheapest listed provider for the Wegovy pill at the 25 mg dose. The comparison tables themselves are always sorted by price — recommendation and ranking are kept separate.
Can I switch to a different injection or a cheaper provider later?
Yes. You buy these treatments four weeks at a time or on a cancellable plan, so you are never locked in. A new provider will run its own consultation and continue you at an appropriate dose rather than restarting. Switching between medicines is also possible, but that is a clinical decision to make with a prescriber.
Comparisons in depth
Best weight-loss injections in the UK: 2026 comparison
Mounjaro, Wegovy or the needle-free pill? We compare UK trial results, side effects and 2026 prices to help you work out which weight-loss injection fits best.
Read the comparison →Weight-loss injection prices compared across 24 UK providers
Mounjaro and Wegovy prices from 24 regulated UK providers, compared dose by dose: cheapest, typical and dearest — plus the extras that change the real cost.
See the numbers →Mounjaro, Wegovy and the rest: what's actually different?
Mounjaro, Wegovy and the new Wegovy pill sound similar but behave differently. The UK's weight-loss injections compared on results, dosing and price.
Understand the difference →Weight-loss injection side effects, compared honestly
Mounjaro, Wegovy and the Wegovy pill share most side effects — but not all. How nausea rates, rare risks and dose ladders compare, in plain English.
Know the trade-offs →How to choose a weight-loss injection: a 5-question framework
Not sure which weight-loss injection to choose? A five-question framework — eligibility, goal, health history, routine and cost — with real UK prices for 2026.
Work through it →